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• In Indianapolis, the Bears ended Indianapolis' remarkable streak of 21 consecutive victories in September and October, marking the first time since 2004 the Colts won't start at least 7-0. Matt Forte, the first Chicago rookie to start at running back since Walter Payton in 1975, ran for 123 yards — 50 on a first-quarter touchdown run in which he broke one tackle and then outran Bob Sanders, last season's defensive player of the year, to the end zone. Kyle Orton, who wrested the starting quarterback job from Rex Grossman, was 13 of 21 for 150 yards and had no turnovers.

• In Foxborough, Mass., New England QB Tom Brady hurt his left knee when he was tackled midway through the first quarter and did not return. Matt Cassel, who had thrown only 39 passes as Brady's backup the past three seasons, took over and completed 13 of 18 passes for 152 yards and one touchdown. The Chiefs moved to the Patriots' 5-yard line with 53 seconds left but finished with two incompletions, a run for no gain and a poorly aimed pass that sailed to the ground wide of the end zone on fourth down.

• In Miami, Brett Favre threw for two TDs and his new beginning had a happy ending thanks to two late defensive stands by the Jets. Dwight Lowery batted away a fourth-down pass in the end zone with nine minutes left, and Darrelle Revis intercepted Chad Pennington in the end zone with five seconds left. Favre finished 15 for 22 for 194 yards and his 161st victory, extending his NFL record for starting quarterbacks.

• In San Diego, Jake Delhomme threw a 14-yard TD pass to tight end Dante Rosario as time expired. capping a desperation drive for the win. After Philip Rivers rallied San Diego with his third TD pass of the game, Delhomme moved the Panthers to the San Diego 14-yard line with two seconds left before calling his final timeout.

• In Nashville, Tenn., the Titans sacked David Garrard seven times, and Cortland Finnegan intercepted him twice in the season opener between the AFC's two wild cards in 2007. Jacksonville had first-and-goal from the Titans' 9 in the final minutes, but Garrard was incomplete on three straight passes, and the Jags settled for a field goal.

• In Pittsburgh, Willie Parker ran for 138 yards and three TDs, and a near-perfect Ben Roethlisberger threw two scoring passes to Hines Ward in a Steelers rout that began with Houston's fourth-down failure on its opening possession. Pittsburgh won its opener for the sixth consecutive season, the NFL's longest current streak.

• In Philadelphia, Donovan McNabb threw for 361 yards and three TDs, and rookie DeSean Jackson had an impressive debut. Jackson, the first Eagles rookie wide receiver to start a season opener in 18 years, had six catches for 106 yards and returned a punt 60 yards to set up a field goal. The Eagles racked up 522 total yards and held the Rams to 109 total yards through three quarters.

• In New Orleans, Drew Brees passed for 343 yards and three TDs, giving fans already jubilant about the Saints' quick return from Hurricane Gustav a triumph to celebrate as well. New Orleans' Scott Fujita intercepted Jeff Garcia's fourth-down pass just inside the Saints' 20 with under 40 seconds to go. Brees' scoring passes went for 39 yards to David Patten, 84 to Devery Henderson and 42 to Reggie Bush, with Bush's score putting the Saints in the lead for good in the fourth quarter.

• In Atlanta, Matt Ryan threw for a TD with his very first NFL pass, and Michael Turner set a team rushing record in his Atlanta debut. The rookie QB electrified the crowd with a 62-yard TD pass to Michael Jenkins to cap the first of three straight scoring drives to open the game. Turner rumbled for 220 yards and two TDs after coming to Atlanta from San Diego in the off-season.

• In Orchard Park, N.Y., Roscoe Parrish scored on a 63-yard punt return, and punter Brian Moorman completed a 19-yard TD pass to defensive end Ryan Denney on a fake field goal attempt, sparking Buffalo to a dominating win. As if that wasn't enough, kicker Rian Lindell recovered a fumble on a kickoff, setting up Trent Edwards' 30-yard TD pass to Robert Royal. Marshawn Lynch also scored on a 21-yard run as the Bills never trailed, and the Bills defense did the rest, holding the Matt Hasselbeck-led Seattle offense to 252 yards.

• In Baltimore, the Ravens forced two turnovers and limited the Bengals to 154 yards to make John Harbaugh a winner in his debut as an NFL coach. Cincinnati QB Carson Palmer was outplayed by Ravens rookie Joe Flacco, forced into the starting role because of a season-ending shoulder injury to Kyle Boller and Troy Smith's infected tonsils. Flacco ran for a 38-yard score to put Baltimore up 17-3 in the third quarter and deftly operated within the careful attack deployed by Harbaugh and new offensive coordinator Cam Cameron.