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Two Phoenix-area philanthropic organizations have committed $45 million to fund an initiative to develop "personalized molecular diagnostics," the use of molecular-level testing to diagnose and treat disease based on a person's unique physiological makeup.

Under the Partnership for Personalized Medicine, the Scottsdale-based Virginia G. Piper Charitable Trust has committed $35 million and the Phoenix-based Flinn Foundation has granted $10 million to fund the effort.

Lee Hartwell, a 2001 Nobel laureate and director of the Fred Hutchinson Cancer Research Center in Seattle, will chair the partnership executive committee, which includes George Poste, director of the Biodesign Institute at Arizona State University, and Dr. Jeffrey Trent, president and scientific director of the Translational Genomics Research Institute, or TGen.

TGen and the Biodesign Institute will contribute laboratory space for the Virginia G. Piper Center for Personalized Diagnostics, which will include an industrial-scale production facility for advanced protein analysis.