Palestinians chant slogans after being prevented from entering the Al-Aqsa Mosque compound for prayers in east Jerusalem's Old City.

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JERUSALEM — Anger over Israeli construction near a disputed Jerusalem holy site erupted into violence Friday as police used tear gas and stun grenades to disperse thousands of rioting Muslims.

Protests spread in the Arab world, with demonstrators accusing Israel of plotting to harm Islamic shrines.

The clashes began after Friday prayers, when Muslims at the site began throwing rocks at police stationed outside, said Jerusalem police spokesman Shmuel Ben Ruby.

About 200 riot police streamed onto the compound, known to Muslims as the Noble Sanctuary and to Jews as the Temple Mount. The officers scuffled with some of the 3,000 Muslim worshippers. Clouds of tear gas rose into the sky and sharp booms pierced the air.

Outside, hundreds of teenagers who had been barred from the Al-Aqsa mosque hurled stones, iron bars, vegetables and at least one firebomb at police, authorities said. Police responded with stun grenades.

The melee slightly injured 17 protesters and 19 police officers, and 17 rioters were arrested, a police spokesman said. Officers shut all the gates leading to the complex, and disconnected loudspeakers they said were used to incite worshippers.

The compound is home to the golden-capped Dome of the Rock shrine and Al-Aqsa mosque. It's believed to be the site where the Prophet Muhammad ascended to heaven. Jews venerate the compound as the site of their biblical temples, and one of its outer walls — known as the Western Wall — is Judaism's holiest site.